Man is an “ecosystem” with 10 13 microorganisms
Modern people often call themselves an island. This may be because people are feeling a little sad, but in physiology, this sentence is true-there are more than 100 million microbial communities in the human body, and the total number of microbes exceeds 10 trillion, covering bacteria, fungi, and viruses. , There are even a small number of archaea that came through from the ancient times.
If the human body is compared to the earth, then the skin, intestines, mouth, respiratory tract and other parts are the African savannahs of microbes. They eat and live together in these places, not only relying on the nourishment of the human body to survive, but also can in turn act on the human body and affect The body functions to form a harmonious ecosystem.
It can be said that everyone’s body is a miracle of life even more miraculous and magnificent than a whale.
Professor Jero Enray from the University of Leuven in Belgium is the world’s top microbiologist. He discovered the relationship between microbes and human depression and said, “You are not only a person, but also a walking flora.”
There are many human ancestors, and microorganisms are one of them. However, seeing this, some people may still be drumming in their hearts: What are they doing to me with so many microorganisms?
What microbes in the body do to us
First, they may change our genes.
It has been discovered that 8% of the sequences in the human genome are derived from retroviruses; some scientists have analyzed that 145 human gene segments are derived from bacteria, viruses and other microorganisms. In other words, the ancestors of contemporary people on earth are not entirely human, and some are bacteria and viruses.
Don’t panic first, these microbial gene fragments have entered the human genome little by little through accidental gene exchange events one after another during the long human evolutionary process.
As for the impact on the human body, it is still unclear. However, anyway, they have existed in the human genome for at least hundreds of thousands of years. They can be regarded as ancestral chromosomes. If you pass them on, you will be safe. If you know your life experience, you can live with a smile.
Although there is no way for the genome, scientists are paying more and more attention to the microorganisms that are still alive on the human body. For example, intestinal flora. Studies have found that when inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis occur, the intestinal flora will also change significantly. The use of probiotics such as bifidobacteria orally to adjust the intestinal flora has a therapeutic effect on many intestinal diseases. This is also the basic operation of gastroenterology and pediatrics for many years.
What is skin microecology?
As we all know, the skin is also an important town where human microorganisms live. Among skin microorganisms, about 74% to 80% are bacteria, 5% to 10% are fungi, and 10% to 20% are viruses. Among them, the most concerned is the role of various bacteria in skin diseases.
From the example of the intestinal tract, we know that adjusting the local microecology can treat and prevent diseases in related parts. Can this experience be applied to the skin?
Just imagine, if you can adjust the microecology on the skin surface by some means, so as to achieve the treatment of skin diseases, and even achieve the effects of whitening, anti-itching, and anti-aging, it will definitely be a means of cognition and treatment of diseases in the field of skin science. Great revolution.
Fortunately, more and more research results illuminate the way for human beings in the regulation of skin microecological.
1013 microbes live in the human body. It is inevitable that they will form cliques, form various forces, squash each other, and play a “game of power”. In some skin diseases, scientists can also achieve therapeutic effects by changing the ratio of skin microbial flora.
Skin diseases that everyone is familiar with, such as acne and dandruff (seborrheic dermatitis), have long been proved to be closely related to microorganisms, and the regulation of microorganisms is the key to the treatment of these diseases.
In addition, although the microbes on the skin are fighting each other, they can still work hand in hand to fight against the enemy and resist external aggression when faced with various pathogenic microbes and air pollutants from the outside world. They can promote the secretion of a class of substances called “antibacterial peptides” by keratinocytes, which can not only kill the pathogens that come up with dead skin, but also have anti-adhesive properties, so that no matter pollutants or pathogens are easy to adhere to the skin, Formed a biological barrier. It can be said that the skin microorganisms are the guards of human beings.
The regulation of skin microecology helps you prevent aging
In the much-anticipated anti-aging aspect, the skin surface flora can also play a role. Just as all over the Internet, oxidative stress is an important cause of skin aging. The bacteria on the skin surface can secrete a powerful antioxidant, which can significantly improve the oxidation of keratinocytes, thereby delaying skin aging. In addition, these antioxidants can also reduce the production of melanin, and may even inhibit the growth of melanocytes. The function is comprehensive and perfect.
In addition to anti-aging and whitening, the important role of skin microorganisms on the human body is to regulate the immune system.
Everyone knows that the immune system is the body’s guard, able to resist foreign substances and biological invasion. Unfortunately, the guards are not born to know who the bad guys are. They only know the skin microbes closest to them. These microorganisms stimulate the immune system again and again, making immune cells highly vigilant, remembering what they look like, and ensuring that they will never be soft when encountering them in the future. The poor immune system has slowly exercised and grown through countless injuries.
What’s interesting is that because everyone’s skin microbiota will change with the external environment, trauma, antibiotic application and other factors, it makes everyone’s skin microbiome unique, so they can give their own immune system unique Stimulation and training. Using this principle, in the future, it may be possible to selectively train the immune system to be allergic or tolerant to certain substances to benefit the majority of patients with allergic diseases.
In addition, the skin flora not only acts on the skin, it can even affect the stability of the intestinal flora. A number of studies have shown that in the intestinal flora of acne patients, the proportion of probiotics such as Clostridium spp. has decreased.
In short, the regulation of skin microecology is currently one of the biggest hotspots in the field of dermatology, and cosmetics, with their convenience and frequency of daily use, have become the trend of this reform. Unfortunately, although everyone knows the importance and broad prospects of this field, there is still a lack of effective control methods. Everyone only dares to explore in the dark, silently preparing their own black technology, looking forward to being the first beam to illuminate the dark The torch made the industry look down on the wind.
In the current research, bacteriophages, as viruses that can swallow bacteria, are considered to be a promising research target because they exist on the surface of the skin and have a targeted effect on bacteria. And foreign cosmetics giants such as L’Oreal have begun to carry out related product research and development many years ago, and have also gained a good reputation in anti-dandruff and helping to improve skin sensitivity.
Maybe in the near future, with the help of technology, we can let the microbe babies work hard like bees, anti-aging day and night, and become the beautiful queen of microbes in our body while talking and laughing.