Clinical studies have found that cardiovascular disease is the leading cause of death among women. Women develop cardiovascular disease about 10 years later than men, but after menopause, the incidence of cardiovascular disease in women is significantly higher.
Estrogen deficiency is the main cause
Estrogen has a direct and indirect protective effect on the cardiovascular system. Estrogen can directly regulate the synthesis and clearance of lipoproteins in the liver and regulate the modification of lipoproteins. It is an important regulator of lipid synthesis and oxidation. Estrogen raises circulating triglyceride (TG) levels by increasing liver secretion of very low-density lipoprotein (VLDL) and decreasing peripheral tissue lipoprotein lipase activity; by upregulating liver low-density lipoprotein (LDL) Receptor expression enhances liver uptake of low-density lipoprotein-cholesterol (LDL-C), which in turn lowers LDL-C levels. Estrogen has strong antioxidant activity and can alleviate the oxidative modification of low density lipoprotein. In addition, estrogen reduces the liver’s uptake of high-density lipoprotein by up-regulating the liver’s synthesis of high-density lipoprotein and apolipoprotein (AI) expression, and reducing hepatic lipoprotein lipase activity.
After menopause, the lack of estrogen can cause dyslipidemia, abnormal glucose metabolism, elevated blood pressure, sympathetic tone, impaired endothelial function and vascular inflammatory response, which means that women are more prone to dyslipidemia after menopause.
Dizziness, fatigue or dyslipidemia
Depending on the degree, the symptoms of dyslipidemia also vary.
Blood lipids rise slightly or fluctuate between normal and abnormal, sometimes without feeling uncomfortable, and it is easy to relax people’s vigilance. Therefore, if you have a family history, a postmenopausal woman, or an older person, it is best to check your blood lipids regularly, even if you don’t have symptoms, so that you can find problems early.
Increased blood lipids for a period of time will affect blood flow, may appear dizziness, fatigue, insomnia, forgetfulness, limb numbness, chest tightness, palpitations and other symptoms. If there are no other diseases, you should be alert to the problem of blood lipids, check as soon as possible, and actively treat. If left untreated, dyslipidemia will develop further, leading to atherosclerosis, which may lead to dizziness, headache, chest tightness, chest pain, shortness of breath, and even severe symptoms such as numbness of the limbs, skewed mouth, and inability to speak. At this time, cardiovascular and cerebrovascular diseases have appeared, which are easy to develop into angina pectoris, myocardial infarction, and stroke, which are serious threats to life and safety.
Blood lipid check four attention
In order to ensure the authenticity of the test results, the following points should be noted before testing blood lipids:
1. Reasonable diet control. Keep the usual eating habits within 2 weeks before the blood draw, do not deliberately adjust the diet, not to eat big fish or deliberately only eat green tofu. Avoid drinking alcohol and eating high-fat foods such as meat or animal internal organs within 3 days before blood draw. Do not eat food for 12 hours before blood draw. It is best not to drink water within 8 hours.
2. It is best to stop the lipid-lowering drugs, contraceptives, hormones and other drugs that can affect blood lipids for several days or weeks before blood collection. If you can’t stop using it, you should tell the doctor to record the drug use as a reference to avoid the drug’s examination. interference.
3. Do not exercise vigorously for 2 to 3 days before testing for blood lipids. Strenuous exercise increases the lipase activity in fat and has a certain effect on blood lipid test results. On the day of the test, you should rest for 5 to 10 minutes before taking the blood test.
4. Infection, trauma, surgery, fever, and women’s menstrual period, pregnancy, etc. will affect blood lipid levels, so it is not recommended to check blood lipids in these cases. If it is necessary to check, the judgment should consider the impact of the above factors on the results.